The kidneys were pale and weighed right, 110 gm., and left, 230 gm.. The surfaces were coarsely and finely granular and punctuated by clear, fluid filled cysts measuring up to 3 cm. in diameter. On the surface of the right kidney there were also 2 yellow, firm, friable raised areas measuring up to 2 cm. in diameter. Microscopically, both kidneys showed many small cortical scars in which there was glomerular and interstitial fibrosis, tubular atrophy, and an infiltration of lymphocytes and plasma cells. Occasional tubules contained hyaline casts admixed with neutrophils. Throughout, there were marked arteriolosclerosis and hyalinization of afferent glomerular arterioles. These changes were more marked in the atrophic right kidney than in the left. In addition, there were 2 small papillary adenomas in the right kidney.

The bone of the vertebral bodies, ribs, and sternum was soft and was easily compressed. The marrow of the vertebral bodies was pale and showed areas of fatty replacement. Microscopically, there were many areas of hypercellularity alternating with areas of hypocellularity. The cells of the erythroid, myeloid, and megakaryocytic series were normal except for their numbers. There was no evidence of fibrosis. The muscles of the extremities, chest wall, neck, and abdominal wall were soft, pale, and atrophic.

Microscopic studies of the gastrocnemius, pectoralis major, transversus abdominis, biceps brachii, and diaphragm showed atrophy as well as varying degrees of injury ranging from swelling and vacuolization to focal necrosis of the muscle fibers. These changes were most marked in the gastrocnemius and biceps and less evident in the pectoralis, diaphragm, and transversus.